4-Sulfonamide Phenylhydrazine Hydrochloride (4SPH)

About 4-Sulfonamide Phenylhydrazine Hydrochloride (4SPH)

4Sulfonamide Phenylhydrazine Hydrochloride

Chemical Overview

Molecular Formula CHClNOS

Molecular Weight 20867 gmol

Functional Groups

Sulfonamide SONH

Phenylhydrazine NHNH

Hydrochloride salt HCl

Structure Properties

This compound consists of

1 Phenylhydrazine core NHNH on a benzene ring known for its reactivity with carbonyl compounds

2 Sulfonamide SONH at the para 4 position confers antibacterial and bioactive properties

3 Hydrochloride salt HCl form increases water solubility and stability

Applications

1 Pharmaceutical Medicinal Chemistry

Potential antimicrobial agent due to the sulfonamide group

May act as a precursor or intermediate in drug synthesis

Related to phenylhydrazine derivatives which interact with ketones and aldehydes

2 Analytical Chemistry

Could be used in derivatization reactions for detecting carbonylcontaining compounds

3 Biochemical Research

Phenylhydrazine derivatives have been studied for their effects on oxidative stress and enzyme inhibition

Reactivity Safety

Reactivity

Can form hydrazones with aldehydesketones

Sulfonamide group can participate in hydrogen bonding affecting drugreceptor interactions

Toxicity Handling

Phenylhydrazines are known to be toxic and potentially mutagenic

Handle with gloves eye protection and a fume hood