Product Description
RPhenylethylamine also known as R1phenylethanamine is a chiral amine with significant roles in organic chemistry pharmaceuticals and as a biochemical precursor Heres a detailed overview
Chemical Details
Molecular Formula C8H11N
Molecular Weight 12118 gmol
Structure
A phenyl ring attached to a chiral ethylamine group
The Rconfiguration refers to the specific spatial arrangement of substituents around the chiral center
Physical Properties
Appearance Colorless to pale yellow liquid
Boiling Point 185C
Optical Rotation Positive D value depends on the solvent and concentration
Biochemical and Pharmacological Context
1 Natural Occurrence
Phenylethylamine is a trace amine found in small amounts in the human brain and other tissues It plays a role in modulating neurotransmitter systems particularly dopamine and serotonin
2 Activity of the REnantiomer
The Renantiomer often has specific binding properties with enzymes and receptors compared to its Scounterpart This stereospecific interaction can influence its pharmacological effects
3 Potential Applications
Neuromodulation Acts as a stimulant of the central nervous system CNS by influencing catecholamine signaling
Drug Precursor Used in the synthesis of pharmaceutical compounds including decongestants antidepressants and weight loss drugs
Applications in Organic Synthesis
Chiral Building Block
Its amine functionality and chirality make it a valuable intermediate for synthesizing enantiomerically pure drugs and materials
Resolution of Racemic Mixtures
Often resolved from racemic phenylethylamine using chiral acids eg tartaric acid or asymmetric synthesis
Pharmaceutical and Industrial Uses
Pharmacological Research
Studies focus on its psychoactive effects and its role as a neuromodulator
Intermediate in Drug Development
Derivatives are used in developing sympathomimetic drugs and other therapeutic agents
Custom Synthesis
Key in synthesizing compounds with adrenergic receptor activity
Safety and Handling
Toxicity May cause irritation to the skin eyes or respiratory system upon exposure Psychoactive effects at high doses
Precautions Handle in a wellventilated environment using gloves and protective eyewear
Would you like details on its synthesis derivatives or specific applications
Exceptional Chiral Purity for Precision SynthesisOur (R)-(+) alpha-Phenylethylamine delivers over 99% enantiomeric excess, making it the preferred choice for asymmetric synthesis in pharmaceutical and fine chemical industries. Its consistent, high purity minimizes unwanted by-products and enhances yield in critical applications.
Versatile Solubility and StabilityThe product's excellent solubility profile in ethanol, ether, and water increases its suitability across various reaction conditions. Storing the liquid in a cool, dry, and well-ventilated space maintains its integrity-even under challenging environments-ensuring reliable results batch after batch.
Secure Packaging and Convenient SupplyWe supply (R)-(+) alpha-Phenylethylamine in robust glass bottles and HDPE drums. Each container is designed to protect the product from contamination and physical hazards, catering to both small-scale and large-volume industrial requirements across India.
FAQ's of (R)-(+) alpha-phenylethylamine:
Q: How should (R)-(+) alpha-phenylethylamine be stored to maintain its quality?
A: The product should be kept tightly closed in a cool, dry, and well-ventilated place to preserve its stability and prevent contamination or degradation.
Q: What are the primary uses of (R)-(+) alpha-phenylethylamine?
A: It serves as an intermediate in the synthesis of pharmaceuticals and fine chemicals, particularly where chiral purity is critical for the end product's efficacy and safety.
Q: When is (R)-(+) alpha-phenylethylamine preferred in chemical synthesis?
A: It is particularly chosen for reactions or processes demanding high enantiomeric purity, such as in the preparation of chiral drugs or specialty chemicals.
Q: Where can this product be supplied or delivered?
A: (R)-(+) alpha-phenylethylamine is distributed and supplied throughout India via reliable manufacturer, supplier, and trader channels.
Q: What packaging options are available for this product?
A: Depending on customer needs, the compound is available in glass bottles and HDPE drums, which ensure safe storage and convenient handling during transportation and use.
Q: How is the quality and purity of this product assured?
A: The product has an assay of 98% (by GC) and chiral purity (ee) greater than 99%, ensuring high quality and reproducibility for sensitive applications.
Q: What are the benefits of using (R)-(+) alpha-phenylethylamine in synthesis?
A: Its high chiral purity, robust stability, and versatile solubility profile make it ideal for reliable and efficient synthesis of high-value pharmaceuticals and advanced materials.